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KMID : 0363220070450040387
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Korean Journal of Dermatology
2007 Volume.45 No. 4 p.387 ~ p.390
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A Case of Pigmented Neurofibroma Associated with Giant Cafe-au-lait Patches
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Lee Yeong-Kyu
Ku Bon-Seok
Lee Chae-Wook
Kim Ki-Ho
Kim Young-Hun
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Abstract
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Pigmented neurofibroma is a rare cutaneous tumor accounting for less than 1% of all neurofibroma. It is characterized histologically by the coexistence of scattered melanin-laden cells and benign spindle cells with neural differentiation. The origin of these tumors are unknown, and they show a storifom pattern. In our case, the patient had giant cafe au lait patches on the left trunk which had been present since birth, freckles on both axilla, and two dark-red colored plaques which had appeared 2 years ago. Histologic examination revealed pigmented neurofibromas showing the melanin-laden, pigmented cells within the upper dermis and plexiform neurofibromas in the subcutaneous tissue. We describe a case of pigmented neurofbroma in a 13-year-old male patient.
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KEYWORD
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Giant Cafe-au-lait Patches, Melanin-laden pigmented cells, Pigmented Neurofibroma
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